منابع مشابه
Intact motility as a Salmonella typhi invasion-related factor.
Invasiveness of Salmonella typhi was investigated. At first, we introduced Tn5 into the chromosome of a wild-type S. typhi strain, GIFU 10007, and screened the independent Tn5 insertion mutants for noninvasive (Inv-) strains. During the first half of this work, we obtained 4 Inv- strains from 1,338 independent Tn5 mutants. The four were either nonflagellate (Fla-), nonmotile (Mot-), or nonchemo...
متن کاملEnvironmental regulation of Salmonella typhi invasion-defective mutants.
Salmonella typhi is the etiologic agent of human typhoid. During infection, S. typhi adheres to and invades epithelial and M cells that line the distal ileum. To survive in the human host, S. typhi must overcome numerous complex extracellular and intracellular environments. Since relatively little is known about S. typhi pathogenesis, studies were initiated to identify S. typhi genes involved i...
متن کاملin Salmonella typhi
S.typhi ompSI constitutes a novel porùt gene. It has seven putative OmpR-binrling boxes and three promoters. Our current model for expression contempLates activation of transcription, from Pl, by OmpR-bindùtg to boxes II anct III (Ctype, low affinity); whereas boxes I and IV-VII would be ùwolved in negative regulation. The fact that ompSI expression increases more thayt 100-foçt upon removal of...
متن کاملPrediction of Toxin-Antitoxin system (TA system) as a Novel Potent Target in Salmonella typhi Using Bioinformatics Analysis
Background and Objective: Salmonella typhi is one of the major challenges for the human and animal health. Salmonella with high pathogenicity can be harmful factor for human health. The control of this pathogen is a big challenge as it can cause serious infectious diseases such as gastroenteritis, septicemia and typhoid fever. On the other side, there are many factors such as toxin-antitoxin (T...
متن کاملSalmonella typhi and Pregnancy: A Case Report
BACKGROUND Salmonella typhi may be a cause of significant morbidity and mortality in both the mother and fetus. Febrile illness during pregnancy, especially that associated with hemolysis, is associated with chorioamnionitis, pyelonephritis, or viral syndrome. As such, S. typhi should be considered when a patient presents with a fever and hemolysis. We present a case of S. typhi complicating pr...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1988
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.56.8.1967-1973.1988